Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 7/20 | 0.69 |
| ▸ | DNMT3A | Q9Y6K1 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | DNMT3L | Q9UJW3 | 4/20 | 0.54 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | AURKA | O14965 | 2/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24006109 | 1.00 | DNMT1 (0.69) | DNMT1DNMT3AKMT2AUSP2MAPT | |
| SCHEMBL30287675 | 1.00 | DNMT1 (0.69) | DNMT1DNMT3AKMT2AUSP2MAPT | |
| SCHEMBL30287678 | 1.00 | DNMT1 (0.69) | DNMT1DNMT3AKMT2AUSP2MAPT | |
| SCHEMBL30290960 | 0.96 | DNMT1 (0.62) | DNMT1DNMT3AKMT2AUSP2MAPT | |
| SCHEMBL24010213 | 0.96 | DNMT1 (0.62) | DNMT1DNMT3AKMT2AUSP2MAPT | |
| SCHEMBL19151334 | 0.96 | DNMT1 (0.62) | DNMT1DNMT3AKMT2AUSP2MAPT | |
| SCHEMBL30290801 | 0.96 | DNMT1 (0.62) | DNMT1DNMT3AKMT2AUSP2MAPT | |
| SCHEMBL24005986 | 0.94 | DNMT1 (0.74) | DNMT1DNMT3AKMT2AUSP2MAPT | |
| SCHEMBL24010923 | 0.93 | DNMT1 (0.59) | DNMT1DNMT3AKMT2AUSP2MAPT | |
| SCHEMBL30290925 | 0.93 | DNMT1 (0.59) | DNMT1DNMT3AKMT2AUSP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-09-21 | — | — | US | disclosed |
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |
| WO-2021226517-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2021-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295114-A1 | AKT3 MODULATORS | AKT3, AKT2, MTOR | DNMT1 4758/4885DNMT3A 4679/4885KMT2A 3925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.