Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | PRKACG | P22612 | 1/20 | 0.36 |
| ▸ | PRKACB | P22694 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 6/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5054635 | 0.79 | HTR2A (0.37) | PRKACAPRKACGPRKACBHTR2CHTR2B | |
| SCHEMBL29748038 | 0.79 | HTR2C (0.43) | PRKACAPRKACGPRKACBHTR2CSLC6A2 | |
| SCHEMBL30463847 | 0.79 | PRKACA (0.45) | PRKACAPRKACGPRKACBSLC6A2SLC6A3 | |
| SCHEMBL23136984 | 0.79 | PRKACA (0.45) | PRKACAPRKACGPRKACBSLC6A2SLC6A3 | |
| SCHEMBL20319860 | 0.79 | TAAR1 (0.38) | PRKACAPRKACGPRKACBHTR2CSLC6A2 | |
| SCHEMBL11138422 | 0.79 | HTR2C (0.43) | PRKACAPRKACGPRKACBHTR2CSLC6A2 | |
| Bromide SCHEMBL27223601 | 0.78 | KDM1A (0.37) | PRKACAPRKACGPRKACBHTR2CSLC6A2 | |
| Bromide SCHEMBL27232096 | 0.78 | KDM1A (0.37) | PRKACAPRKACGPRKACBHTR2CSLC6A2 | |
| Hydrochloric Acid SCHEMBL31444540 | 0.78 | HTR2C (0.39) | PRKACAPRKACGPRKACBHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL31444535 | 0.78 | HTR2A (0.39) | PRKACAPRKACGPRKACBHTR2COPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |