Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dbpr-108 SCHEMBL2401277 | 0.99 | DPP4 (1.00) | DPP4 | |
| Dbpr-108 SCHEMBL3404362 | 0.99 | DPP4 (1.00) | DPP4 | |
| SCHEMBL2401017 | 0.89 | DPP4 (1.00) | DPP4 | |
| SCHEMBL8007213 | 0.89 | DPP4 (0.89) | DPP4 | |
| SCHEMBL2399922 | 0.89 | DPP4 (1.00) | DPP4 | |
| SCHEMBL2399916 | 0.89 | DPP4 (1.00) | DPP4 | |
| SCHEMBL2402389 | 0.87 | DPP4 (1.00) | DPP4 | |
| SCHEMBL2398904 | 0.87 | DPP4 (1.00) | DPP4 | |
| SCHEMBL2401026 | 0.86 | DPP4 (1.00) | DPP4 | |
| SCHEMBL2401032 | 0.86 | DPP4 (1.00) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252582-B1 | PYRROLIDINE DERIVATIVES | NAT HEALTH RESEARCH INSTITUTES (TW) | 2014-07-23 | — | — | EP | disclosed |
| EP-2252582-B1 | PYRROLIDINE DERIVATIVES | NAT HEALTH RESEARCH INSTITUTES (TW) | 2014-07-23 | — | — | EP | disclosed |
| US-8022096-B2 | Pyrrolidine derivatives | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-09-20 | — | — | US | disclosed |
| US-8022096-B2 | Pyrrolidine derivatives | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-09-20 | — | — | US | disclosed |
| US-8022096-B2 | Pyrrolidine derivatives | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-09-20 | — | — | US | disclosed |
| WO-2009111239-A2 | PYRROLIDINE DERIVATIVES | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-09-11 | — | — | WO | disclosed |
| US-20090227569-A1 | PYRROLIDINE DERIVATIVES | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-09-10 | — | — | US | disclosed |
| US-20090227569-A1 | PYRROLIDINE DERIVATIVES | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-09-10 | — | — | US | disclosed |
| US-20090227569-A1 | PYRROLIDINE DERIVATIVES | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227569-A1 | PYRROLIDINE DERIVATIVES | DPP4, DPP7, DPP3 | DPP4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.