Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25824173 | 0.88 | KMT2A (0.57) | MAPTSMN1; SMN2KMT2AMAPK1KDM4E | |
| SCHEMBL23999691 | 0.88 | IP6K1 (0.46) | MAPTKMT2AMAPK1KDM4EALDH1A1 | |
| SCHEMBL24003938 | 0.88 | IP6K1 (0.43) | MAPTKMT2AMAPK1KDM4EALDH1A1 | |
| SCHEMBL25826715 | 0.85 | MAPT (0.52) | MAPTSMN1; SMN2KMT2AMAPK1KDM4E | |
| SCHEMBL24003898 | 0.84 | LATS1 (0.39) | MAPTSMN1; SMN2KMT2AMAPK1KDM4E | |
| SCHEMBL24010843 | 0.84 | MAPT (0.53) | MAPTSMN1; SMN2KMT2AMAPK1KDM4E | |
| SCHEMBL29125302 | 0.80 | MAPT (0.48) | MAPTSMN1; SMN2KMT2AMAPK1KDM4E | |
| SCHEMBL25466142 | 0.80 | KDM4E (0.43) | MAPTSMN1; SMN2KMT2AMAPK1KDM4E | |
| SCHEMBL23999557 | 0.80 | KMT2A (0.54) | MAPTSMN1; SMN2KMT2AMAPK1KDM4E | |
| SCHEMBL29125442 | 0.80 | KMT2A (0.57) | MAPTSMN1; SMN2KMT2AMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226477-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2021-11-11 | — | — | WO | disclosed |