Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 9/20 | 1.00 |
| ▸ | FUCA1 | P04066 | 4/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | GLB1 | P16278 | 1/20 | 0.52 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1627889 | 1.00 | GBA1 (1.00) | GBA1FUCA1GLAGAAGLB1 | |
| SCHEMBL18628805 | 1.00 | GBA1 (1.00) | GBA1FUCA1GLAGAAGLB1 | |
| SCHEMBL1627508 | 1.00 | GBA1 (1.00) | GBA1FUCA1GLAGAAGLB1 | |
| SCHEMBL6435045 | 1.00 | GBA1 (1.00) | GBA1FUCA1GLAGAAGLB1 | |
| SCHEMBL1628218 | 1.00 | GBA1 (1.00) | GBA1FUCA1GLAGAAGLB1 | |
| SCHEMBL7405332 | 0.86 | — | — | |
| SCHEMBL6431779 | 0.84 | GBA1 (0.72) | GBA1FUCA1GLAGAAGLB1 | |
| SCHEMBL20016401 | 0.84 | GBA1 (0.72) | GBA1FUCA1GLAGAAGLB1 | |
| SCHEMBL6856714 | 0.84 | GBA1 (0.72) | GBA1FUCA1GLAGAAGLB1 | |
| SCHEMBL17578923 | 0.80 | GBA1 (1.00) | GBA1FUCA1GLAGAAGLB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226330-A1 | AGENTS TO PREVENT TISSUE DAMAGE FROM CLOSTRIDIUM DIFFICILE INFECTIONS BY INHIBITION OF THE GUT-DAMAGING BACTERIAL TOXINS TCDA AND TCDB | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2021-11-11 | — | — | WO | disclosed |