Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24813423 | 0.97 | KDR (0.52) | BRAFKDR | |
| SCHEMBL24007044 | 0.93 | BRAF (0.48) | BRAFKDR | |
| SCHEMBL24007891 | 0.93 | BRAF (0.49) | BRAFKDR | |
| SCHEMBL24374954 | 0.90 | BRAF (0.60) | BRAFKDR | |
| SCHEMBL24007717 | 0.89 | ABL1 (0.57) | BRAFKDR | |
| SCHEMBL24007593 | 0.86 | ABL1 (0.58) | BRAFKDR | |
| SCHEMBL24007131 | 0.85 | BRAF (0.49) | BRAFKDR | |
| SCHEMBL25592323 | 0.84 | BRAF (0.57) | BRAFKDR | |
| SCHEMBL23795601 | 0.83 | BRAF (0.56) | BRAFKDR | |
| SCHEMBL24813420 | 0.83 | RAF1 (0.63) | BRAFKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226261-A1 | 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS | AJAX THERAPEUTICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |