Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 3/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | GAK | O14976 | 2/20 | 0.41 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.41 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.41 |
| ▸ | EPHA8 | P29322 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.41 |
| ▸ | COQ8A | Q8NI60 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25606792 | 0.93 | PDPK1 (0.47) | PDGFRAPDGFRBTRPA1SRCTGFBR1 | |
| SCHEMBL24837347 | 0.88 | PDGFRA (0.55) | PDGFRAPDGFRBFGFR2EGFRKDR | |
| SCHEMBL1496287 | 0.86 | PDGFRB (0.57) | PDGFRAPDGFRBSRCTGFBR1FGFR2 | |
| SCHEMBL12503594 | 0.84 | PDGFRB (0.47) | PDGFRAPDGFRBSRCTGFBR1FGFR2 | |
| Methane SCHEMBL24557063 | 0.83 | PDGFRB (0.46) | PDGFRAPDGFRBSRCTGFBR1FGFR2 | |
| SCHEMBL5233653 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2ACVR1 | |
| SCHEMBL24008901 | 0.82 | RET (0.44) | PDGFRAPDGFRBTRPA1FGFR2EGFR | |
| SCHEMBL6004195 | 0.82 | SRC (0.48) | PDGFRAPDGFRBTRPA1SRCFGFR2 | |
| SCHEMBL30430404 | 0.82 | RET (0.44) | PDGFRAPDGFRBTRPA1FGFR2EGFR | |
| SCHEMBL14540912 | 0.80 | SRC (0.46) | PDGFRAPDGFRBSRCTGFBR1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021225969-A1 | IMINO SULFANONE INHIBITORS OF ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |