⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23777 | 0.72 | — | — | |
| SCHEMBL23044067 | 0.61 | — | — | |
| SCHEMBL2339 | 0.61 | — | — | |
| SCHEMBL127813 | 0.61 | — | — | |
| SCHEMBL6113934 | 0.55 | — | — | |
| SCHEMBL23961 | 0.55 | — | — | |
| Hydrochloric Acid SCHEMBL9799153 | 0.55 | — | — | |
| Water SCHEMBL25365379 | 0.55 | — | — | |
| SCHEMBL11038950 | 0.55 | — | — | |
| SCHEMBL26810 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2965 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024109922-A1 | BRIDGED RING PYRIDAZINE COMPOUND AND USE THEREOF | 成都赜灵生物医药科技有限公司 | 2024-05-30 | — | — | WO | claimed |
| CN-117402091-A | Synthetic method of sodium monofluoromethylsulfinate | 瑞博(杭州)医药科技有限公司 | 2024-01-16 | — | — | CN | claimed |
| CN-112724055-B | Method for synthesizing aromatic monofluoromethylthio compounds by one-pot method | 南京理工大学 | 2022-06-07 | — | — | CN | claimed |
| CN-112724055-A | Method for synthesizing aromatic monofluoromethylthio compounds by one-pot method | 南京理工大学 | 2021-04-30 | — | — | CN | claimed |
| CN-111909144-A | Quinazoline DNA-PK inhibitor | 山东轩竹医药科技有限公司 | 2020-11-10 | — | — | CN | claimed |
| US-10028942-B2 | 3-substituted pyrazoles and uses thereof | GENENTECH, INC. (US) | 2018-07-24 | — | — | US | claimed |
| EP-2945938-B1 | 3-SUBSTITUTED PYRAZOLES AND USE AS DLK INHIBITORS | HOFFMANN LA ROCHE (CH) | 2018-03-07 | — | — | EP | claimed |
| US-20170087137-A1 | 3-SUBSTITUTED PYRAZOLES AND USES THEREOF | GENENTECH, INC. (US) | 2017-03-30 | — | — | US | claimed |
| US-9550777-B2 | 3-substituted pyrazoles and use as DLK inhibitors | GENENTECH, INC. (US) | 2017-01-24 | — | — | US | claimed |
| WO-2016174049-A1 | ANTI-PARASITIC COMBINATIONS INCLUDING HALOGEN-SUBSTITUTED COMPOUNDS | BAYER ANIMAL HEALTH GMBH (DE) | 2016-11-03 | — | — | WO | claimed |
| EP-0264021-A2 | 0-Aryl-N'-(triazin-2-yl)-isourea | BAYER AG (DE) | 1988-04-20 | — | — | EP | claimed |
| EP-0246534-A2 | Optically pure 4,5-disubstituted gamma-butyrolactame enantiomers, process for their preparation and their use | BAYER AG (DE) | 1987-11-25 | — | — | EP | claimed |
| US-4650809-A | AGRICULTURE | BAYER AKTIENGESELLSCHAFT (DE) | 1987-03-17 | — | — | US | claimed |
| EP-0132680-B1 | SUBSTITUTED FURAZANS | BAYER AG (DE) | 1987-01-28 | — | — | EP | claimed |
| EP-0118070-B1 | SUBSTITUTED 1,3-DIAZOLYL-2-PROPANOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTIMYCOTIC COMPOUNDS | BAYER AG (DE) | 1986-10-08 | — | — | EP | claimed |
| EP-0070464-B1 | SUBSTITUTED PHENYLCYCLOPROPANECARBOXYLIC-ACID ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES | BAYER AG (DE) | 1985-10-02 | — | — | EP | claimed |
| EP-0040573-B1 | 2-SUBSTITUTED-4-HYDROXY-3-QUINOLINECARBOXYLIC ACIDS, THEIR PREPARATION, THEIR USE AS MEDICAMENTS, COMPOSITIONS CONTAINING THEM AND INTERMEDIATES | ROUSSEL-UCLAF (FR) | 1984-08-01 | — | — | EP | claimed |
| EP-0045980-B1 | COMPOUNDS USEFUL IN THE PREPARATION OF AMINOPIPERIDINES WITH ANORECTIC PROPERTIES | SANOFI S.A. (FR) | 1983-10-05 | — | — | EP | claimed |
| EP-0012639-A2 | Quinolein-3-carboxylic acid derivatives, process for their preparation, their use in medicines and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1980-06-25 | — | — | EP | claimed |
| US-4010179-A | ANTIMICROBIAL, ANTINEOPLASTIC | AMERICAN CYANAMID COMPANY (US) | 1977-03-01 | — | — | US | claimed |