Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 4/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26633858 | 0.92 | EPHX1 (0.49) | EPHX1MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL24011083 | 0.92 | EPHX1 (0.57) | EPHX1MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL24011473 | 0.84 | EPHX1 (0.62) | EPHX1HPGDRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL26633885 | 0.83 | EPHX1 (0.49) | EPHX1MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL30634118 | 0.83 | EPHX1 (0.49) | EPHX1MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL24011339 | 0.82 | EPHX1 (0.64) | EPHX1MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL24011243 | 0.81 | EPHX1 (0.57) | EPHX1MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL24011233 | 0.81 | TSHR (0.68) | EPHX1MAPTSMN1; SMN2TSHRKMT2A | |
| SCHEMBL24011533 | 0.77 | EPHX1 (0.58) | EPHX1MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL24011075 | 0.77 | EPHX1 (0.58) | EPHX1HPGDRAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| WO-2021226276-A2 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | EPHX1 3913/4885MAPT 582/4885HPGD 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.