Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | LSS | P48449 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26633753 | 0.89 | MCHR1 (0.54) | MCHR1HRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24011262 | 0.88 | MCHR1 (0.58) | MCHR1HRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24011321 | 0.86 | MCHR1 (0.53) | MCHR1HRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24011294 | 0.85 | SMN1; SMN2 (0.58) | MCHR1HRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24011436 | 0.85 | SMN1; SMN2 (0.63) | MCHR1HRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24011437 | 0.85 | SMN1; SMN2 (0.63) | MCHR1HRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14456766 | 0.84 | CYP3A4 (0.67) | CYP3A4CYP2D6LSSCYP2C9TSHR | |
| SCHEMBL24011390 | 0.83 | SMN1; SMN2 (0.56) | MCHR1HRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24011257 | 0.82 | SMN1; SMN2 (0.65) | MCHR1HRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24011062 | 0.82 | SMN1; SMN2 (0.59) | MCHR1HRH3NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| WO-2021226276-A2 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | MCHR1 360/4885HRH3 1432/4885NPC1 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.