Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.76 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.76 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.76 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | PER2 | O15055 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19139015 | 0.88 | HDAC6 (0.84) | HDAC6HDAC2HDAC8TBXA2RPTGDR | |
| SCHEMBL19138945 | 0.88 | HDAC6 (0.84) | HDAC6HDAC2HDAC8TBXA2RPTGDR | |
| SCHEMBL17520608 | 0.87 | HDAC2 (0.73) | HDAC6HDAC2HDAC8TBXA2RPTGDR | |
| SCHEMBL19161125 | 0.87 | HDAC6 (0.81) | HDAC6HDAC2HDAC8TBXA2RPTGDR | |
| SCHEMBL17500260 | 0.87 | HDAC6 (1.00) | HDAC6HDAC2HDAC8TBXA2RPTGDR | |
| SCHEMBL19161134 | 0.85 | HDAC6 (0.77) | HDAC6HDAC2HDAC8TBXA2RPTGDR | |
| SCHEMBL19138888 | 0.83 | HDAC6 (0.81) | HDAC6HDAC2HDAC8TBXA2RPTGDR | |
| SCHEMBL17500240 | 0.82 | HDAC6 (1.00) | HDAC6HDAC2HDAC8HDAC1HDAC10 | |
| SCHEMBL19162216 | 0.80 | HDAC6 (0.73) | HDAC6HDAC2HDAC8TBXA2RPTGDR | |
| SCHEMBL19138997 | 0.79 | HDAC6 (0.76) | HDAC6HDAC2HDAC8TBXA2RPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177621-B1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | UNIV REGENSBURG (DE) | 2021-11-10 | — | — | EP | disclosed |