Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 20/20 | 0.75 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.75 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.75 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17520642 | 0.85 | HDAC6 (1.00) | HDAC6HDAC2HDAC8HDAC1HDAC4 | |
| SCHEMBL17500188 | 0.78 | HDAC6 (1.00) | HDAC6HDAC2HDAC8HDAC1HDAC4 | |
| SCHEMBL17520641 | 0.77 | HDAC6 (0.85) | HDAC6HDAC2HDAC8HDAC1HDAC4 | |
| SCHEMBL12951762 | 0.76 | HDAC6 (1.00) | HDAC6HDAC2HDAC8HDAC1HDAC4 | |
| SCHEMBL24012180 | 0.75 | HDAC6 (0.81) | HDAC6HDAC2HDAC8HDAC1HDAC4 | |
| SCHEMBL19138950 | 0.74 | HDAC6 (1.00) | HDAC6HDAC2HDAC8HDAC1HDAC4 | |
| SCHEMBL19166369 | 0.74 | HDAC6 (1.00) | HDAC6HDAC2HDAC8HDAC1HDAC4 | |
| SCHEMBL19167610 | 0.74 | HDAC6 (0.86) | HDAC6HDAC2HDAC8HDAC1HDAC4 | |
| SCHEMBL17520534 | 0.74 | HDAC6 (1.00) | HDAC6HDAC2HDAC8HDAC1HDAC4 | |
| SCHEMBL19138927 | 0.74 | HDAC6 (1.00) | HDAC6HDAC2HDAC8HDAC1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177621-B1 | NOVEL HDAC6 INHIBITORS AND THEIR USES | UNIV REGENSBURG (DE) | 2021-11-10 | — | — | EP | disclosed |