Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 19/20 | 0.56 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24012294 | 0.92 | KLKB1 (0.55) | KLKB1 | |
| SCHEMBL24569820 | 0.90 | KLKB1 (0.55) | KLKB1 | |
| SCHEMBL22685022 | 0.88 | KLKB1 (0.56) | KLKB1 | |
| SCHEMBL20584646 | 0.87 | KLKB1 (0.74) | KLKB1 | |
| SCHEMBL29581508 | 0.87 | KLKB1 (0.74) | KLKB1 | |
| SCHEMBL21726714 | 0.86 | KLKB1 (0.45) | KLKB1UCHL1 | |
| SCHEMBL20584372 | 0.86 | KLKB1 (0.45) | KLKB1UCHL1 | |
| SCHEMBL20446649 | 0.86 | KLKB1 (0.45) | KLKB1UCHL1 | |
| SCHEMBL22685920 | 0.86 | KLKB1 (0.45) | KLKB1UCHL1 | |
| SCHEMBL29489465 | 0.86 | KLKB1 (0.45) | KLKB1UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4019022-A1 | HUMAN PLASMA KALLIKREIN INHIBITORS | BioCryst Pharmaceuticals, Inc. (US) | 2022-06-29 | — | — | EP | disclosed |
| EP-3355890-B1 | HUMAN PLASMA KALLIKREIN INHIBITORS | BIOCRYST PHARM INC (US) | 2021-11-10 | — | — | EP | disclosed |