Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 2/20 | 0.57 |
| ▸ | CDC25B | P30305 | 2/20 | 0.57 |
| ▸ | CDC25C | P30307 | 2/20 | 0.57 |
| ▸ | S100A4 | P26447 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | USP19 | O94966 | 1/20 | 0.33 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2404412 | 0.89 | CDC25A (0.60) | CDC25ACDC25BCDC25CS100A4MAPK14 | |
| SCHEMBL1918993 | 0.89 | CDC25A (0.71) | CDC25ACDC25BCDC25CS100A4MAPK14 | |
| SCHEMBL2398596 | 0.87 | CDC25A (0.50) | CDC25ACDC25BCDC25CS100A4MALT1 | |
| SCHEMBL2401595 | 0.84 | CDC25A (0.82) | CDC25ACDC25BCDC25CS100A4MAPK14 | |
| SCHEMBL2398528 | 0.83 | CDC25A (0.50) | CDC25ACDC25BCDC25CS100A4MAPK14 | |
| SCHEMBL1918245 | 0.83 | CDC25A (0.66) | CDC25ACDC25BCDC25CS100A4MAPK14 | |
| SCHEMBL2401246 | 0.82 | CDC25A (0.49) | CDC25ACDC25BCDC25CS100A4USP1 | |
| SCHEMBL2401747 | 0.82 | CDC25A (0.49) | CDC25ACDC25BCDC25CS100A4USP1 | |
| SCHEMBL2403256 | 0.82 | CDC25A (0.52) | CDC25ACDC25BCDC25CS100A4SLC9A1 | |
| SCHEMBL2400556 | 0.81 | CDC25A (0.48) | CDC25ACDC25BCDC25CS100A4MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275624-A1 | INHIBITORS OF CDC PHOSPHATASES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2009-11-05 | — | — | US | claimed |
| EP-1831209-B1 | CDC25 PHOSPHATASE INHIBITORS | IPSEN PHARMA (FR) | 2009-08-12 | — | — | EP | claimed |
| US-8017637-B2 | Inhibitors of cdc phosphatases | IPSEN PHARMA S.A.S. (FR) | 2011-09-13 | — | — | US | disclosed |
| US-20090275624-A1 | INHIBITORS OF CDC PHOSPHATASES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2009-11-05 | — | — | US | disclosed |
| EP-1831209-B1 | CDC25 PHOSPHATASE INHIBITORS | IPSEN PHARMA (FR) | 2009-08-12 | — | — | EP | disclosed |
| EP-1831209-A2 | CDC25 PHOSPHATASE INHIBITORS | Société de Conseils de Recherches et d'Applications Scientifiques SAS (S.C.R.A.S) (FR) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006067311-A2 | CDC25 PHOSPHATASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) SAS (FR) | 2006-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275624-A1 | INHIBITORS OF CDC PHOSPHATASES | CDC25C, CDC25A, CDC25B | CDC25A 2/4885CDC25B 3/4885CDC25C 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.