Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24012643 | 0.92 | BRD4 (0.38) | BRD4L3MBTL1MAPTHTR3AKMT2A | |
| SCHEMBL30242740 | 0.91 | BRD4 (0.40) | BRD4L3MBTL1MAPTHTR3AKMT2A | |
| SCHEMBL24013053 | 0.91 | BRD4 (0.40) | BRD4L3MBTL1MAPTHTR3AKMT2A | |
| SCHEMBL24012702 | 0.90 | BRD4 (0.39) | BRD4L3MBTL1MAPTHTR3AKMT2A | |
| SCHEMBL26741107 | 0.90 | BRD4 (0.38) | BRD4L3MBTL1MAPTHTR3AKMT2A | |
| SCHEMBL30242656 | 0.90 | BRD4 (0.41) | BRD4L3MBTL1MAPTHTR3AKDM4E | |
| SCHEMBL30242724 | 0.90 | BRD4 (0.39) | BRD4L3MBTL1MAPTHTR3AKMT2A | |
| SCHEMBL24012476 | 0.90 | BRD4 (0.39) | BRD4L3MBTL1MAPTHTR3AKMT2A | |
| SCHEMBL24013067 | 0.90 | BRD4 (0.41) | BRD4L3MBTL1MAPTHTR3AKDM4E | |
| SCHEMBL24012985 | 0.89 | BRD4 (0.38) | BRD4L3MBTL1MAPTHTR3AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021224320-A1 | NEW MACROCYCLIC LRRK2 KINASE INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2021-11-11 | — | — | WO | disclosed |