Methacrylic Acid

Methacrylic Acid

SCHEMBL2401419

C=C(C)C(=O)O.C=C(CO)C(=O)O

nearest known ligand 0.43

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 5/20 0.39
TET3 O43151 1/20 0.37
TET1 Q8NFU7 1/20 0.37
OR51E2 Q9H255 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
GRIK1 P39086 1/20 0.36
GRIK2 Q13002 1/20 0.36
GRM1 Q13255 1/20 0.36
GRM2 Q14416 1/20 0.36
ALOX15 P16050 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TGFBR1 P36897 1/20 0.35
ALDH1A1 P00352 1/20 0.32
FFAR3 O14843 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL136796 0.88
Methacrylic Acid SCHEMBL148580 0.88 TDP1 (0.44) TET2TET3TET1OR51E2TDP1
Methacrylic Acid SCHEMBL3779015 0.88 TDP1 (0.44) TET2TET3TET1OR51E2TDP1
Methacrylic Acid SCHEMBL7638155 0.85 TDP1 (0.42) TET2TET3TET1OR51E2TDP1
SCHEMBL8935074 0.85
Ammonia Solution, Strong SCHEMBL11784573 0.85
SCHEMBL15010320 0.85
SCHEMBL11785793 0.85
Water SCHEMBL26128700 0.85 OR51E2 (0.42) TET2TET3TET1OR51E2GRIK1
Methacrylic Acid SCHEMBL11035054 0.82 TDP1 (0.40) TET2OR51E2TDP1ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102481322-A Bacterial compositions for prophylaxis and treatment of degenerative disease MICROPHARMA LTD 2012-05-30 CN claimed
US-8012461-B2 Biofilm remover Wireley Corporation Pty Ltd (AU) 2011-09-06 US disclosed
US-20080317877-A1 Biofilm Remover WHITELEY CORPORATION PTY. LTD. (AU) 2008-12-25 US disclosed
WO-2005120592-A1 BIOFILM REMOVER WHITELEY CORPORATION PTY LTD (AU) 2005-12-22 WO disclosed