SCHEMBL2401765

SCHEMBL2401765

CNC(C)=O.CNC(C)=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.54
CA2 P00918 1/20 0.54
PTGS1 P23219 1/20 0.54
MMP12 P39900 1/20 0.54
NFKB1 P19838 1/20 0.50
LMNA P02545 2/20 0.46
ALDH1A1 P00352 3/20 0.43
TSHR P16473 2/20 0.42
THPO P40225 1/20 0.42
FFAR3 O14843 1/20 0.42
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
CRBN Q96SW2 1/20 0.41
MCL1 Q07820 1/20 0.40
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
MMP8 P22894 1/20 0.39
CA1 P00915 2/20 0.39
ALOX15 P16050 1/20 0.39
BLM P54132 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4397 1.00
SCHEMBL18510170 1.00
SCHEMBL20411614 1.00
SCHEMBL8063647 0.95
Methyl Alcohol SCHEMBL10966612 0.95
Lithium SCHEMBL668450 0.95
Ammonia Solution, Strong SCHEMBL10746719 0.95
SCHEMBL10956055 0.95
Bromide SCHEMBL6544774 0.95
Hydrochloric Acid SCHEMBL28372971 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0604882-B1 Semipermeable membranes made of homogeneous mixable polymeric alloys HOECHST AG (DE) 1998-08-26 EP claimed
US-5505851-A Semipermeable membranes of homogeneously miscible polymer alloys HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-09 US claimed
CN-118792016-A Organosilicon coolant containing phase change component and preparation method thereof 宁波市鄞州特尔斐电子有限公司 2024-10-18 CN disclosed
US-8187319-B2 Porous synthetic vascular grafts with oriented ingrowth channels MEDTRONIC, INC. (US) 2012-05-29 US disclosed
US-20110213454-A1 Porous Synthetic Vascular Grafts with Oriented Ingrowth Channels MEDTRONIC, INC. 2011-09-01 US disclosed
US-7727274-B2 Porous synthetic vascular grafts with oriented ingrowth channels MEDTRONIC, INC. (US) 2010-06-01 US disclosed
US-7632306-B2 Foam-type vascular prosthesis with well-defined angio-permissive open porosity MEDTRONIC, INC. (US) 2009-12-15 US disclosed
EP-1616532-B1 Method of manufacturing porous synthetic vascular grafts with oriented ingrowth channels MEDTRONIC INC (US) 2008-02-27 EP disclosed
US-20060149358-A1 Porous synthetic vascular grafts with oriented ingrowth channels MEDTRONIC, INC. (US) 2006-07-06 US disclosed
EP-1669044-A2 Foam-type vascular prosthesis with well-defined angio-permissive open porosity Medtronic, Inc. (US) 2006-06-14 EP disclosed
EP-1202683-B1 FOAM-TYPE VASCULAR PROSTHESIS WITH WELL-DEFINED ANGIO-PERMISSIVE OPEN POROSITY MEDTRONIC INC (US) 2006-05-17 EP disclosed
US-20040006383-A1 Foam-type vascular prosthesis with well-defined angio-permissive open porosity MEDTRONIC, INC. 2004-01-08 US disclosed
US-6616699-B2 Foam-type vascular prosthesis with well-defined angio-permissive open porosity ZILLA PETER PAUL (ZA) 2003-09-09 US disclosed
US-6540780-B1 Porous synthetic vascular grafts with oriented ingrowth channels MEDTRONIC, INC. 2003-04-01 US disclosed
US-20020169499-A1 Porous synthetic vascular grafts with oriented ingrowth channels MEDTRONIC, INC. 2002-11-14 US disclosed
EP-1202683-A1 FOAM-TYPE VASCULAR PROSTHESIS WITH WELL-DEFINED ANGIO-PERMISSIVE OPEN POROSITY MEDTRONIC, INC. (US) 2002-05-08 EP disclosed
US-20010002444-A1 Foam-type vascular prosthesis with well-defined angio-permissive open porosity MEDTRONIC, INC. 2001-05-31 US disclosed
WO-2001005333-A1 FOAM-TYPE VASCULAR PROSTHESIS WITH WELL-DEFINED ANGIO-PERMISSIVE OPEN POROSITY MEDTRONIC, INC. (US) 2001-01-25 WO disclosed
EP-1049422-A1 POROUS SYNTHETIC VASCULAR GRAFTS WITH ORIENTED INGROWTH CHANNELS MEDTRONIC, INC. (US) 2000-11-08 EP disclosed
WO-2000030564-A2 POROUS SYNTHETIC VASCULAR GRAFTS WITH ORIENTED INGROWTH CHANNELS MEDTRONIC, INC. (US) 2000-06-02 WO disclosed