Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 20/20 | 0.83 |
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.83 |
| ▸ | TLR8 | Q9NR97 | 19/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21967936 | 0.92 | TLR9 (0.84) | TLR9TLR7TLR8 | |
| SCHEMBL19952224 | 0.91 | TLR9 (1.00) | TLR9TLR7TLR8 | |
| SCHEMBL29584931 | 0.91 | TLR9 (1.00) | TLR9TLR7TLR8 | |
| SCHEMBL29585042 | 0.89 | TLR9 (1.00) | TLR9TLR7TLR8 | |
| SCHEMBL19951757 | 0.89 | TLR9 (1.00) | TLR9TLR7TLR8 | |
| SCHEMBL19952577 | 0.88 | TLR9 (1.00) | TLR9TLR7TLR8 | |
| SCHEMBL29584002 | 0.88 | TLR9 (1.00) | TLR9TLR7TLR8 | |
| SCHEMBL29585562 | 0.88 | TLR9 (1.00) | TLR9TLR7TLR8 | |
| SCHEMBL19951810 | 0.88 | TLR9 (1.00) | TLR9TLR7TLR8 | |
| SCHEMBL19952656 | 0.87 | TLR9 (0.79) | TLR9TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3510024-B1 | PYRIDYL SUBSTITUTED INDOLE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-11-17 | — | — | EP | disclosed |