⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7184750 | 0.73 | TSHR (0.31) | — | |
| SCHEMBL3281118 | 0.68 | TSHR (0.40) | — | |
| SCHEMBL2121872 | 0.68 | TSHR (0.56) | — | |
| SCHEMBL8406999 | 0.67 | — | — | |
| SCHEMBL23985 | 0.66 | — | — | |
| SCHEMBL11880055 | 0.66 | — | — | |
| SCHEMBL13616194 | 0.66 | — | — | |
| SCHEMBL8472259 | 0.65 | CHRM1 (0.40) | — | |
| SCHEMBL12518006 | 0.64 | — | — | |
| SCHEMBL9093559 | 0.64 | TSHR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016126757-A1 | METHODS FOR PREPARATION OF MACROCYCLIC POLYESTER OLIGOMER FROM LINEAR POLYESTER | LIQUID THERMO PLASTICS, INC. (US) | 2016-08-11 | — | — | WO | disclosed |
| EP-2678371-B1 | METHODS FOR PREPARATION OF MACROCYCLIC POLYESTER OLIGOMER VIA HETEROGENEOUS CATALYSIS | CYCLICS CORP (US) | 2015-01-07 | — | — | EP | disclosed |
| US-20140378644-A1 | METHODS FOR PREPARATION OF MACROCYCLIC POLYESTER OLIGOMER VIA HETEROGENEOUS CATALYSIS | LIQUID THERMO PLASTICS INC (US) | 2014-12-25 | — | — | US | disclosed |
| US-8829152-B2 | Methods for preparation of macrocyclic polyester oligomer via heterogeneous catalysis | LIQUID THERMO PLASTICS, INC. (US) | 2014-09-09 | — | — | US | disclosed |
| US-20120302721-A1 | Methods for Preparation of Macrocyclic Polyester Oligomer via Heterogeneous Catalysis | LIQUID THERMO PLASTICS, INC. | 2012-11-29 | — | — | US | disclosed |
| WO-2012145065-A1 | METHODS FOR PREPARATION OF MACROCYCLIC POLYESTER OLIGOMER VIA HETEROGENEOUS CATALYSIS | CYCLICS CORPORATION (US) | 2012-10-26 | — | — | WO | disclosed |
| US-8283437-B2 | Preparation of low-acid polyalkylene terephthalate and preparation of macrocyclic polyester oligomer therefrom | CYCLICS CORPORATION (US) | 2012-10-09 | — | — | US | disclosed |
| US-20110213116-A1 | PREPARATION OF LOW-ACID POLYALKYLENE TEREPHTHALATE AND PREPARATION OF MACROCYCLIC POLYESTER OLIGOMER THEREFROM | LIQUID THERMO PLASTICS, INC. | 2011-09-01 | — | — | US | disclosed |
| US-7767781-B2 | Preparation of low-acid polyalkylene terephthalate and preparation of macrocyclic polyester oligomer therefrom | CYCLICS CORPORATION (US) | 2010-08-03 | — | — | US | disclosed |
| US-7750109-B2 | Use of a residual oligomer recyclate in the production of macrocyclic polyester oligomer | CYCLICS CORPORATION (US) | 2010-07-06 | — | — | US | disclosed |
| US-7732557-B2 | Methods for removing catalyst residue from a depolymerization process stream | CYCLICS CORPORATION (US) | 2010-06-08 | — | — | US | disclosed |
| EP-1879940-A1 | PREPARATION OF LOW-ACID POLYALKYLENE TEREPHTHALATE AND PREPARATION OF MACROCYCLIC POLYESTER OLIGOMER THEREFROM | Cyclics Corporation (US) | 2008-01-23 | — | — | EP | disclosed |
| US-20060235233-A1 | Methods for removing catalyst residue from a depolymerization process stream | CYCLICS CORPORATION (US) | 2006-10-19 | — | — | US | disclosed |
| US-20060235186-A1 | Use of a residual oligomer recyclate in the production of macrocyclic polyester oligomer | CYCLICS CORPORATION (US) | 2006-10-19 | — | — | US | disclosed |
| US-20060235185-A1 | Preparation of low-acid polyalkylene terephthalate and preparation of macrocyclic polyester oligomer therefrom | CYCLICS CORPORATION (US) | 2006-10-19 | — | — | US | disclosed |
| WO-2006104821-A1 | PREPARATION OF LOW-ACID POLYALKYLENE TEREPHTHALATE AND PREPARATION OF MACROCYCLIC POLYESTER OLIGOMER THEREFROM | CYCLICS CORPORAITON (US) | 2006-10-05 | — | — | WO | disclosed |