Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22957777 | 0.85 | AXL (0.43) | MCHR1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL29786569 | 0.83 | CSNK2A1 (0.44) | MCHR1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL16793239 | 0.83 | CSNK2A1 (0.44) | MCHR1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL22957686 | 0.82 | NPY1R (0.53) | PDE4DPDE4APDE4BPDE4CSLC6A2 | |
| SCHEMBL24180099 | 0.79 | PDE4D (0.41) | MCHR1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL22389471 | 0.77 | PDE4D (0.39) | MCHR1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL17164061 | 0.74 | MCHR1 (0.49) | MCHR1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8223783 | 0.73 | TAAR1 (0.43) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL28422963 | 0.73 | SLC6A2 (0.64) | MCHR1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL9538522 | 0.72 | SLC6A2 (0.56) | MCHR1PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3580220-B1 | AMINOTRIAZOLOPYRIDINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-11-17 | — | — | EP | disclosed |