Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2399693 | 0.90 | ESR2 (0.53) | ESR2ESR1 | |
| SCHEMBL12266842 | 0.86 | ESR2 (0.50) | ESR2ESR1 | |
| SCHEMBL3930667 | 0.84 | ESR2 (0.68) | ESR2ESR1 | |
| SCHEMBL4733697 | 0.83 | ESR2 (0.67) | ESR2ESR1 | |
| SCHEMBL4733695 | 0.83 | ESR2 (0.67) | ESR2ESR1 | |
| SCHEMBL4736120 | 0.82 | ESR2 (0.68) | ESR2ESR1 | |
| SCHEMBL2397415 | 0.82 | ESR2 (0.68) | ESR2ESR1 | |
| Prinaberel SCHEMBL1379424 | 0.81 | ESR2 (1.00) | ESR2ESR1 | |
| SCHEMBL2400099 | 0.81 | ESR2 (0.67) | ESR2ESR1 | |
| SCHEMBL14032925 | 0.81 | ESR2 (0.67) | ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212923-A1 | Phosphate Derivatives of Substituted Benzoxazoles | PFIZER INC. | 2011-09-01 | — | — | US | claimed |
| US-20110212923-A1 | Phosphate Derivatives of Substituted Benzoxazoles | PFIZER INC. | 2011-09-01 | — | — | US | disclosed |
| EP-2250180-A1 | PHOSPHATE DERIVATIVES OF SUBSTITUTED BENZOXAZOLES | Wyeth LLC (US) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009100335-A1 | PHOSPHATE DERIVATIVES OF SUBSTITUTED BENZOXAZOLES | WYETH (US) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212923-A1 | Phosphate Derivatives of Substituted Benzoxazoles | ESR2, GPER1, ESR1 | ESR2 1/4885ESR1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.