SCHEMBL24022176

SCHEMBL24022176

Cc1ccccc1C1=C(c2ccc(OC3CCN(CCCF)C3)cc2)c2ccc(N)cc2CCC1

nearest known ligand 0.84

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 20/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23335914 1.00 ESR1 (0.84) ESR1
SCHEMBL24022037 0.92 ESR1 (0.73) ESR1
SCHEMBL21253433 0.92 ESR1 (0.84) ESR1
SCHEMBL21252976 0.91 ESR1 (0.84) ESR1
SCHEMBL21253333 0.91 ESR1 (0.84) ESR1
SCHEMBL19132597 0.91 ESR1 (1.00) ESR1
SCHEMBL24022015 0.91 ESR1 (0.72) ESR1
SCHEMBL21252900 0.91 ESR1 (0.86) ESR1
SCHEMBL24022193 0.91 ESR1 (0.84) ESR1
SCHEMBL24022023 0.91 ESR1 (0.83) ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3524600-B1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF NOVEL SUBSTITUTED 6,7-DIHYDRO-5H-BENZO[7]ANNULENE COMPOUNDS SANOFI SA (FR) 2021-11-17 EP disclosed