Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10172791 | 0.94 | TSHR (0.50) | TSHRLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL19821798 | 0.85 | TSHR (0.52) | TSHRLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL12439225 | 0.82 | TSHR (0.54) | TSHRLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL16707218 | 0.82 | TSHR (0.58) | TSHRLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL7538601 | 0.80 | TSHR (0.47) | TSHRLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL25645496 | 0.80 | TSHR (0.32) | TSHRLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL29268609 | 0.79 | TSHR (0.45) | TSHRLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL3733099 | 0.78 | TSHR (0.44) | TSHRLMNAALDH1A1MAPTKMT2A | |
| Isobutanol SCHEMBL8024741 | 0.77 | TSHR (0.64) | TSHRLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL8798185 | 0.77 | TSHR (0.52) | TSHRLMNAALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2214716-B1 | HYDROXYAPATITE-TARGETING MULTIARM POLYMERS AND CONJUGATES MADE THEREFROM | NEKTAR THERAPEUTICS (US) | 2021-11-17 | — | — | EP | disclosed |