SCHEMBL24026445

SCHEMBL24026445

C/C=C\C(O)=C/C=C/C(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.35
ESR2 Q92731 6/20 0.35
PDCD1 Q15116 1/20 0.35
CD274 Q9NZQ7 1/20 0.35
LMNA P02545 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32
ADORA3 P0DMS8 2/20 0.32
CYP2D6 P10635 2/20 0.32
MAPT P10636 2/20 0.32
CYP2C9 P11712 2/20 0.32
ALOX15 P16050 2/20 0.32
CYP2C19 P33261 2/20 0.32
PGR P06401 1/20 0.32
CHRM2 P08172 1/20 0.32
AR P10275 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD1 P21728 1/20 0.32
TBXA2R P21731 1/20 0.32
PTGS1 P23219 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3719178 0.76 ESR1 (0.48) ESR1ESR2PDCD1CD274LMNA
SCHEMBL109077 0.76 ESR1 (0.48) ESR1ESR2PDCD1CD274LMNA
SCHEMBL12755322 0.74 APP (0.52) ESR1ESR2LMNACYP1A2CYP3A4
SCHEMBL1082595 0.73 IDO1 (0.44) ESR1ESR2PDCD1CD274LMNA
SCHEMBL15721460 0.69 ESR1 (0.38) ESR1ESR2LMNACYP3A4AR
SCHEMBL30777839 0.69 MAPT (0.48) ESR1ESR2PDCD1CD274LMNA
SCHEMBL24181239 0.65 PELI1 (0.35) ESR1ESR2TDP1
SCHEMBL12510761 0.64
SCHEMBL16542594 0.64
SCHEMBL15128064 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3909997-A1 RESIN COMPOSITION, METHOD FOR PRODUCING SAID RESIN COMPOSITION, AND THERMALLY CONDUCTIVE SHEET Nitto Shinko Corporation (JP) 2021-11-17 EP disclosed