Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 2/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15083754 | 0.88 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL19583170 | 0.87 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL15068393 | 0.87 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2C19 | |
| SCHEMBL19600203 | 0.87 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2C19 | |
| SCHEMBL21271519 | 0.87 | CYP1A2 (0.54) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2C19 | |
| SCHEMBL15065399 | 0.85 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2C19 | |
| SCHEMBL19605454 | 0.85 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2C19 | |
| SCHEMBL19606106 | 0.85 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2C19 | |
| SCHEMBL25022433 | 0.85 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2C19 | |
| SCHEMBL30382604 | 0.85 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3909941-A1 | INTERMEDIATES OF 2-HYDROXY-6-((2-(1-ISOPROPYL-1H-PYRAZOL-5-YL)-PYRIDIN-3-YL)METHOXY)BENZALDEHYDE | Global Blood Therapeutics, Inc. (US) | 2021-11-17 | — | — | EP | disclosed |