Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10303819 | 1.00 | ABAT (0.39) | ABATMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL17744754 | 0.84 | POLB (0.38) | ABATMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL27341 | 0.76 | MAPT (0.37) | MEN1KMT2ATDP1ALDH1A1POLB | |
| SCHEMBL22390581 | 0.76 | MAPT (0.37) | MEN1KMT2ATDP1ALDH1A1POLB | |
| SCHEMBL5585363 | 0.76 | MAPT (0.37) | MEN1KMT2ATDP1ALDH1A1POLB | |
| SCHEMBL10739512 | 0.75 | POLB (0.54) | MEN1KMT2ATDP1ALDH1A1POLB | |
| SCHEMBL60588 | 0.75 | POLB (0.54) | MEN1KMT2ATDP1ALDH1A1POLB | |
| SCHEMBL10739509 | 0.75 | POLB (0.54) | MEN1KMT2ATDP1ALDH1A1POLB | |
| SCHEMBL31737192 | 0.75 | POLB (0.54) | MEN1KMT2ATDP1ALDH1A1POLB | |
| SCHEMBL14433706 | 0.75 | POLB (0.54) | MEN1KMT2ATDP1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11441163-B2 | Enzyme-catalyzed synthesis of (1S,5R)-bicyclolactone | FUDAN UNIVERSITY (CN) | 2022-09-13 | — | — | US | disclosed |
| US-20210355516-A1 | ENZYME-CATALYZED SYNTHESIS OF (1S,5R)-BICYCLOLACTONE | FUDAN UNIVERSITY (CN) | 2021-11-18 | — | — | US | disclosed |