SCHEMBL24029087

SCHEMBL24029087

CC(C)CCC(=O)N[C@H](C(=O)N[C@@H](CCCCNC(N)=O)C(=O)Nc1ccc(CC(C)C)cc1)C(C)C

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ TRPV1 Q8NER1 5/20 0.43
▸ NPY5R Q15761 5/20 0.41
▸ NPY4R P50391 5/20 0.41
▸ NPY1R P25929 4/20 0.41
▸ NPY2R P49146 2/20 0.41
▸ FURIN P09958 2/20 0.41
▸ CALCRL Q16602 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ SIRT5 Q9NXA8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22336348 0.97 TRPV1 (0.44) TRPV1NPY5RNPY4RNPY1RNPY2R
SCHEMBL22336351 0.97 TRPV1 (0.44) TRPV1NPY5RNPY4RNPY1RNPY2R
SCHEMBL21754508 0.93 NPY4R (0.47) TRPV1NPY5RNPY4RNPY1RNPY2R
SCHEMBL25826708 0.93 NPY4R (0.47) TRPV1NPY5RNPY4RNPY1RNPY2R
SCHEMBL24496678 0.91 TRPV1 (0.42) TRPV1NPY5RNPY4RNPY1RNPY2R
SCHEMBL23815045 0.91 CHRND (0.44) TRPV1NPY5RNPY4RNPY1RNPY2R
SCHEMBL22746602 0.90 TRPV1 (0.42) TRPV1NPY5RNPY4RNPY1RNPY2R
SCHEMBL24496495 0.90 TRPV1 (0.45) TRPV1NPY5RNPY4RNPY1RNPY2R
SCHEMBL27432789 0.89 NPY4R (0.44) TRPV1NPY5RNPY4RNPY1RNPY2R
SCHEMBL27432923 0.89 NPY4R (0.44) TRPV1NPY5RNPY4RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210355230-A1 USE OF ANTI-CD5 ANTIBODY DRUG CONJUGATE (ADC) IN ALLOGENEIC CELL THERAPY HEIDELBERG PHARMA RESEARCH GMBH (DE) 2021-11-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210355230-A1 USE OF ANTI-CD5 ANTIBODY DRUG CONJUGATE (ADC) IN ALLOGENEIC CELL THERAPY CD59, CD58, CD2 TRPV1 2565/4885NPY5R 2455/4885NPY4R 3682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback