Sugi Predict

Sugi Predict / Compounds / SCHEMBL24029769

SCHEMBL24029769

SCHEMBL24029769

C#CCN(C)C(=O)CN(C)CCNC(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CHRM2 P08172 2/20 0.40
▸ CHRM4 P08173 2/20 0.40
▸ CHRM5 P08912 2/20 0.40
▸ CHRM1 P11229 2/20 0.40
▸ CHRM3 P20309 2/20 0.40
▸ TDP1 Q9NUW8 1/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ CTSL P07711 1/20 0.36
▸ CTSB P07858 1/20 0.36
▸ CTSS P25774 1/20 0.36
▸ CKS1B P61024 1/20 0.35
▸ SKP1 P63208 1/20 0.35
▸ SKP2 Q13309 1/20 0.35
▸ MAOA P21397 1/20 0.35
▸ MAOB P27338 1/20 0.35
▸ CA12 O43570 2/20 0.34
▸ CA1 P00915 2/20 0.34
▸ CA2 P00918 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24029771 0.88 CHRM2 (0.34) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL3250569 0.86 TDP1 (0.45) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL15032996 0.83 CHRM2 (0.47) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL26550964 0.82 POLB (0.31) —
SCHEMBL24029924 0.82 TDP1 (0.46) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL24029756 0.80 — —
SCHEMBL631279 0.79 TDP1 (0.46) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL13055395 0.78 TDP1 (0.55) TDP1MEN1GAAKMT2ACKS1B
SCHEMBL1404486 0.77 MEN1 (0.49) TDP1MEN1GAAKMT2ACKS1B
SCHEMBL24029827 0.76 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365610-A1 Aryl Glucoside Derivative SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2023-11-16 — — US disclosed
US-20230331760-A1 ARYL GLUCOSIDE DERIVATIVE AND USE THEREOF IN DRUG SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2023-10-19 — — US disclosed
US-20230331761-A1 Aryl Glucoside Derivative, Preparation Method Therefor And Application Thereof SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2023-10-19 — — US disclosed
WO-2021227439-A1 ARYL GLUCOSIDE DERIVATIVE 上海喆邺生物科技有限公司 2021-11-18 — — WO disclosed
WO-2021227441-A1 ARYL GLUCOSIDE DERIVATIVE AND USE THEREOF IN DRUG 上海喆邺生物科技有限公司 2021-11-18 — — WO disclosed
WO-2021227440-A1 A CLASS OF ARYL GLUCOSIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 上海喆邺生物科技有限公司 2021-11-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331761-A1 Aryl Glucoside Derivative, Preparation Method Therefor And Application Thereof SLC5A1, SLC5A2, SLC10A1 CHRM2 4157/4885CHRM4 4182/4885CHRM5 4539/4885
US-20230331760-A1 ARYL GLUCOSIDE DERIVATIVE AND USE THEREOF IN DRUG SLC5A1, SLC5A2, SLC10A1 CHRM2 4416/4885CHRM4 4218/4885CHRM5 4767/4885
US-20230365610-A1 Aryl Glucoside Derivative SLC5A1, SLC5A2, SLC10A1 CHRM2 3153/4885CHRM4 3543/4885CHRM5 3769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.