SCHEMBL24029918

SCHEMBL24029918

C#CCN(C)C(=O)CN1CCN(C(=O)C(C)(C)NC(=O)COCc2ccc(Cc3cc([C@@H]4O[C@H](SC)[C@@H](O)[C@H](O)[C@H]4O)ccc3C)cc2)CC1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC5A1 P13866 18/20 0.59
SLC5A2 P31639 12/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24029879 0.94 SLC5A1 (0.62) SLC5A1SLC5A2
SCHEMBL24029549 0.90 SLC5A1 (0.75) SLC5A1SLC5A2
SCHEMBL24029928 0.89 SLC5A1 (0.71) SLC5A1SLC5A2
SCHEMBL24029910 0.89 SLC5A1 (0.72) SLC5A1SLC5A2
SCHEMBL24029832 0.89 SLC5A1 (0.45) SLC5A1SLC5A2
SCHEMBL24029831 0.89 SLC5A1 (0.45) SLC5A1SLC5A2
SCHEMBL24030128 0.88 SLC5A1 (0.58) SLC5A1SLC5A2
SCHEMBL24029548 0.87 SLC5A1 (0.52) SLC5A1SLC5A2
SCHEMBL24029880 0.87 SLC5A1 (0.52) SLC5A1SLC5A2
SCHEMBL24029917 0.84 SLC5A1 (0.62) SLC5A1SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230331761-A1 Aryl Glucoside Derivative, Preparation Method Therefor And Application Thereof SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2023-10-19 US disclosed
US-20230331761-A1 Aryl Glucoside Derivative, Preparation Method Therefor And Application Thereof SHANGHAI ZHEYE BIOTECHNOLOGY CO. LTD. (CN) 2023-10-19 US disclosed
WO-2021227440-A1 A CLASS OF ARYL GLUCOSIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 上海喆邺生物科技有限公司 2021-11-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331761-A1 Aryl Glucoside Derivative, Preparation Method Therefor And Application Thereof SLC5A1, SLC5A2, SLC10A1 SLC5A1 1/4885SLC5A2 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.