Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 15/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30040744 | 0.97 | PTPN11 (0.69) | PTPN11KCNH2EGFRSCN9A | |
| SCHEMBL24033795 | 0.97 | PTPN11 (0.69) | PTPN11KCNH2EGFRSCN9A | |
| SCHEMBL30040098 | 0.82 | PTPN11 (0.69) | PTPN11KCNH2EGFRSCN9A | |
| SCHEMBL24033796 | 0.82 | PTPN11 (0.69) | PTPN11KCNH2EGFRSCN9A | |
| SCHEMBL30041299 | 0.81 | PTPN11 (0.60) | PTPN11KCNH2EGFR | |
| SCHEMBL24033797 | 0.81 | PTPN11 (0.60) | PTPN11KCNH2EGFR | |
| SCHEMBL30041436 | 0.80 | PTPN11 (0.49) | PTPN11KCNH2EGFR | |
| SCHEMBL24034409 | 0.80 | PTPN11 (0.49) | PTPN11KCNH2EGFR | |
| SCHEMBL24034239 | 0.80 | PTPN11 (0.61) | PTPN11KCNH2EGFRSCN9A | |
| SCHEMBL30040568 | 0.80 | PTPN11 (0.61) | PTPN11KCNH2EGFRSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210355105-A1 | REGULATOR OF NITROGEN-CONTAINING HETEROAROMATIC DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210355105-A1 | REGULATOR OF NITROGEN-CONTAINING HETEROAROMATIC DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | PTPN11, PTPN1, PTPN7 | PTPN11 1/4885KCNH2 4613/4885EGFR 1050/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.