Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30950320 | 1.00 | PTPN11 (0.60) | PTPN11 | |
| SCHEMBL30950323 | 0.87 | PTPN11 (0.70) | PTPN11 | |
| SCHEMBL30041324 | 0.87 | PTPN11 (0.61) | PTPN11 | |
| SCHEMBL24034408 | 0.87 | PTPN11 (0.61) | PTPN11 | |
| SCHEMBL19785501 | 0.84 | PTPN11 (0.60) | PTPN11 | |
| SCHEMBL30295904 | 0.84 | PTPN11 (0.60) | PTPN11 | |
| SCHEMBL21115106 | 0.81 | PTPN11 (0.70) | PTPN11 | |
| SCHEMBL21115110 | 0.81 | PTPN11 (0.70) | PTPN11 | |
| SCHEMBL21115076 | 0.81 | PTPN11 (0.62) | PTPN11 | |
| SCHEMBL21115074 | 0.81 | PTPN11 (0.62) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210355105-A1 | REGULATOR OF NITROGEN-CONTAINING HETEROAROMATIC DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210355105-A1 | REGULATOR OF NITROGEN-CONTAINING HETEROAROMATIC DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | PTPN11, PTPN1, PTPN7 | PTPN11 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.