SCHEMBL24036628

SCHEMBL24036628

c1ccc(-c2ccc3ccc(-c4ccc(-c5ccccc5)c5ccccc45)cc3c2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.57
ESR2 Q92731 6/20 0.57
GSTP1 P09211 1/20 0.45
MAP4K4 O95819 1/20 0.44
TYK2 P29597 1/20 0.44
MINK1 Q8N4C8 1/20 0.44
SRPK1 Q96SB4 1/20 0.44
CLK4 Q9HAZ1 1/20 0.44
BACE1 P56817 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
HSD17B1 P14061 2/20 0.42
HSD17B2 P37059 2/20 0.42
MEN1 O00255 2/20 0.42
NPC1 O15118 2/20 0.42
MAPT P10636 2/20 0.42
KMT2A Q03164 2/20 0.42
APAF1 O14727 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22414174 0.85 ESR1 (0.47) ESR1ESR2GSTP1MAP4K4TYK2
SCHEMBL22987051 0.84 ESR1 (0.46) ESR1ESR2MAP4K4TYK2MINK1
SCHEMBL27511439 0.84 ESR1 (0.74) ESR1ESR2CLK4BACE1CA1
SCHEMBL22414173 0.83 MEN1 (0.50) ESR1ESR2GSTP1BACE1CA12
SCHEMBL3193310 0.82 GSTP1 (0.64) ESR1ESR2GSTP1CA1CA2
SCHEMBL20313386 0.82 GSTP1 (0.46) ESR1ESR2GSTP1CA12CA1
SCHEMBL15366918 0.82 ESR1 (0.43) ESR1ESR2GSTP1HSD17B1HSD17B2
SCHEMBL25891975 0.82 ESR1 (0.46) ESR1ESR2GSTP1BACE1CA12
SCHEMBL21203617 0.82 ESR1 (0.44) ESR1ESR2GSTP1MAP4K4TYK2
SCHEMBL24377040 0.81 GSTP1 (0.48) ESR1ESR2GSTP1HSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021230651-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-11-18 WO disclosed