Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | ICMT | O60725 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14450386 | 0.86 | CYP1A2 (0.39) | IDO1TDO2SLC17A5ACECASP3 | |
| SCHEMBL12267407 | 0.85 | CYP1A2 (0.40) | MAPTSLC17A5ACECASP3 | |
| SCHEMBL12707836 | 0.85 | CYP1A2 (0.40) | MAPTSLC17A5ACECASP3 | |
| SCHEMBL30341699 | 0.83 | PPARA (0.60) | IDO1MAPTALDH1A1SLC17A5ACE | |
| SCHEMBL8541445 | 0.83 | PPARA (0.60) | IDO1MAPTALDH1A1SLC17A5ACE | |
| SCHEMBL24037243 | 0.83 | PPARA (0.60) | IDO1MAPTALDH1A1SLC17A5ACE | |
| SCHEMBL12065748 | 0.83 | PPARA (0.60) | IDO1MAPTALDH1A1SLC17A5ACE | |
| SCHEMBL19888241 | 0.83 | SLC17A5 (0.58) | SLC17A5CASP3 | |
| SCHEMBL12066256 | 0.81 | SLC17A5 (0.38) | IDO1TDO2SLC17A5ACECASP3 | |
| SCHEMBL14063754 | 0.81 | PPARA (0.58) | IDO1TDO2SLC17A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023152347-A1 | PROCESS FOR MANUFACTURING MACROCYCLIC PEPTIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2023-08-17 | — | — | WO | disclosed |
| US-20210355132-A1 | PREPARATION METHOD FOR ECTEINASCIDIN COMPOUND AND INTERMEDIATE THEREOF | UNIVERSITÉ PARIS CITÉ (FR) | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210355132-A1 | PREPARATION METHOD FOR ECTEINASCIDIN COMPOUND AND INTERMEDIATE THEREOF | TMED9, EMD, ENTPD8 | IDO1 951/4885TDO2 1953/4885ICMT 1594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.