Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21151427 | 0.88 | BRAF (0.44) | BRAF | |
| SCHEMBL21086751 | 0.85 | BRAF (0.50) | BRAF | |
| SCHEMBL3022579 | 0.83 | BRAF (0.64) | BRAF | |
| SCHEMBL24037784 | 0.79 | ABL1 (0.55) | BRAF | |
| SCHEMBL18583694 | 0.76 | BRAF (0.62) | BRAF | |
| SCHEMBL24037896 | 0.74 | BRAF (0.41) | BRAFBRD4 | |
| SCHEMBL3029616 | 0.72 | BRAF (0.66) | BRAF | |
| SCHEMBL21086750 | 0.70 | SMN1; SMN2 (0.42) | BRAF | |
| SCHEMBL3019340 | 0.70 | BRAF (0.61) | BRAF | |
| SCHEMBL3022533 | 0.70 | BRAF (0.63) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210353602-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC (US) | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210353602-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | MAP3K20, MAP3K13, MAP3K8 | BRAF 48/4885BRD4 727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.