Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.51 |
| ▸ | NMT2 | O60551 | 2/20 | 0.40 |
| ▸ | NMT1 | P30419 | 2/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.38 |
| ▸ | CHRNG | P07510 | 1/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.38 |
| ▸ | CHRND | Q07001 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24038735 | 1.00 | GLP1R (0.51) | GLP1RNMT2NMT1SIRT6SIRT1 | |
| SCHEMBL24038551 | 0.95 | GLP1R (0.50) | GLP1RNMT2NMT1SIRT6SIRT1 | |
| SCHEMBL24038550 | 0.95 | GLP1R (0.50) | GLP1RNMT2NMT1SIRT6SIRT1 | |
| SCHEMBL24629763 | 0.85 | NMT1 (0.48) | GLP1RNMT2NMT1SIRT6SIRT1 | |
| SCHEMBL25269706 | 0.85 | GLP1R (0.58) | GLP1RNMT2NMT1SIRT6SIRT1 | |
| SCHEMBL25269707 | 0.85 | GLP1R (0.58) | GLP1RNMT2NMT1SIRT6SIRT1 | |
| SCHEMBL20464133 | 0.84 | GLP1R (0.46) | GLP1RNMT2NMT1TLR2PLK1 | |
| SCHEMBL20450602 | 0.84 | GLP1R (0.46) | GLP1RNMT2NMT1TLR2PLK1 | |
| SCHEMBL20450600 | 0.84 | GLP1R (0.46) | GLP1RNMT2NMT1TLR2PLK1 | |
| SCHEMBL29326161 | 0.84 | NMT1 (0.52) | GLP1RNMT2NMT1SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021228939-A1 | FLUOROGENIC DIMER COMPOUND, USEFUL AS A PROBE FOR DETECTION OF ENDOGENOUS RECEPTORS | UNIVERSITE DE STRASBOURG (FR) | 2021-11-18 | — | — | WO | disclosed |