SCHEMBL24040348

SCHEMBL24040348

CC(C)(C)OC(=O)CCCCCCCCCCCCCCCCC(=O)NC(CCC(=O)ON1C(=O)CCC1O)C(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.40
POLB P06746 1/20 0.36
HDAC8 Q9BY41 1/20 0.32
EPHX2 P34913 1/20 0.31
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31
NOD1 Q9Y239 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
P2RY12 Q9H244 2/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22365183 0.86 CYP1A2 (0.36) KMT2ABCHEACHEMEN1
SCHEMBL20144614 0.85 EPHX2 (0.38) KMT2AHDAC8EPHX2
SCHEMBL1887808 0.84 KMT2A (0.44) KMT2APOLBHDAC8EPHX2NOD1
SCHEMBL20450544 0.84 KMT2A (0.44) KMT2APOLBHDAC8EPHX2NOD1
SCHEMBL1677088 0.84 KMT2A (0.44) KMT2APOLBHDAC8EPHX2NOD1
SCHEMBL24819248 0.84 KMT2A (0.44) KMT2APOLBHDAC8EPHX2NOD1
SCHEMBL20144613 0.84 KMT2A (0.44) KMT2APOLBHDAC8EPHX2NOD1
SCHEMBL20467657 0.84 KMT2A (0.44) KMT2APOLBHDAC8EPHX2NOD1
SCHEMBL20467680 0.84 KMT2A (0.44) KMT2APOLBHDAC8EPHX2NOD1
SCHEMBL26413508 0.84 KMT2A (0.44) KMT2APOLBHDAC8EPHX2NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11179467-B2 Exenatide modifier and use thereof BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO., LTD. (CN) 2021-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11179467-B2 Exenatide modifier and use thereof GLP1R, GCGR, GIPR KMT2A 3214/4885POLB 4799/4885HDAC8 3400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.