Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 8/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.55 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.43 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22256882 | 1.00 | SLCO1B1 (0.67) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL24287686 | 0.87 | SLCO1B1 (0.52) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22256875 | 0.84 | SLCO1B1 (0.64) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL24043052 | 0.84 | SLCO1B1 (0.64) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22256588 | 0.83 | SLCO1B1 (0.68) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL24042781 | 0.83 | SLCO1B1 (0.62) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22256591 | 0.83 | SLCO1B1 (0.67) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22256877 | 0.83 | SLCO1B1 (0.62) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22256605 | 0.82 | SLCO1B1 (0.64) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 | |
| SCHEMBL22256606 | 0.82 | SLCO1B1 (0.73) | SLCO1B1ABCB11LPAR1ABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3912975-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS AND PREPARATION METHOD THEREFOR | Wuhan LL Science And Technology Development Co., Ltd. (CN) | 2021-11-24 | — | — | EP | disclosed |