Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.72 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.59 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.59 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046842 | 0.85 | PPARG (0.78) | PPARGCYP11B1CYP11B2SIGMAR1HTR2B | |
| Flidersiachromone SCHEMBL5826185 | 0.84 | PPARG (1.00) | PPARGCYP11B1CYP11B2SIGMAR1HTR2B | |
| Flidersiachromone SCHEMBL29408800 | 0.84 | PPARG (1.00) | PPARGCYP11B1CYP11B2SIGMAR1HTR2B | |
| SCHEMBL24046786 | 0.78 | PPARG (0.62) | PPARGCYP11B1CYP11B2SIGMAR1HTR2B | |
| SCHEMBL16972870 | 0.77 | PPARG (0.74) | PPARGCYP11B1CYP11B2SIGMAR1HTR2B | |
| SCHEMBL24046838 | 0.76 | PPARG (0.78) | PPARGCYP11B1CYP11B2HTR2BHTR3A | |
| SCHEMBL24227263 | 0.76 | PPARG (0.82) | PPARGCYP11B1CYP11B2SIGMAR1HTR2B | |
| SCHEMBL29128897 | 0.74 | PPARG (0.71) | PPARGCYP11B1VKORC1SIGMAR1HTR2B | |
| SCHEMBL24046779 | 0.74 | PPARG (0.57) | PPARGCYP11B1CYP11B2SIGMAR1HTR2B | |
| SCHEMBL30800378 | 0.74 | PPARG (0.71) | PPARGCYP11B1VKORC1SIGMAR1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |