Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 6/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25855935 | 0.86 | PREP (0.41) | ELANEDPP4DPP8DPP9DPP7 | |
| SCHEMBL18754696 | 0.86 | DPP4 (0.35) | ELANEDPP4DPP8DPP9DPP7 | |
| SCHEMBL13073346 | 0.86 | DPP4 (0.35) | ELANEDPP4DPP8DPP9DPP7 | |
| SCHEMBL13073428 | 0.85 | STAT6 (0.34) | ELANEDPP4DPP8DPP9DPP7 | |
| SCHEMBL25510029 | 0.85 | DPP4 (0.34) | ELANEDPP4DPP8DPP9DPP7 | |
| SCHEMBL13161235 | 0.85 | NPSR1 (0.36) | ELANEDPP4DPP8DPP9DPP7 | |
| SCHEMBL15765626 | 0.84 | DPP4 (0.45) | ELANEDPP4DPP8DPP9DPP7 | |
| SCHEMBL20707055 | 0.84 | DPP4 (0.45) | ELANEDPP4DPP8DPP9DPP7 | |
| SCHEMBL24068280 | 0.84 | VHL (0.35) | ELANEDPP4DPP8DPP9DPP7 | |
| SCHEMBL26749959 | 0.84 | STAT6 (0.38) | ELANEDPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4397661-A1 | COMPOUND FOR DEGRADATION OF BCL-2 FAMILY PROTEINS AND MEDICAL APPLICATION THEREOF | Xizang Haisco Pharmaceutical Co., Ltd. (CN) | 2024-07-10 | — | — | EP | disclosed |
| WO-2024050742-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING KRAS G12D VIA UBIQUITIN PROTEASOME PATHWAY | NIKANG THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
| WO-2021236775-A1 | SMALL MOLECULE DEGRADERS OF SHP2 PROTEIN | THE REGENTS OF THE UNIVERSITY OFMICHIGAN (US) | 2021-11-25 | — | — | WO | disclosed |