Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Picolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Picolamine SCHEMBL11870934 | 1.00 | CHRNA7 (0.65) | — | |
| Picolamine SCHEMBL17850 | 0.98 | — | — | |
| Picolamine SCHEMBL29394769 | 0.98 | — | — | |
| Picolamine SCHEMBL30046657 | 0.98 | — | — | |
| Picolamine SCHEMBL29881286 | 0.95 | CHRNA7 (0.65) | — | |
| Picolamine SCHEMBL5012162 | 0.95 | CHRNA7 (0.65) | — | |
| Picolamine SCHEMBL28805513 | 0.95 | — | — | |
| Picolamine SCHEMBL2674094 | 0.95 | — | — | |
| Picolamine SCHEMBL7984435 | 0.95 | — | — | |
| Picolamine SCHEMBL29880401 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110993798-B | Perovskite type solar cell based on synergistic post-treatment of multiple ammonium salts and preparation thereof | 北京大学 | 2021-11-19 | — | — | CN | claimed |
| CN-110993798-A | Perovskite type solar cell based on cooperative post-treatment of multiple ammonium salts and preparation method thereof | 北京大学 | 2020-04-10 | — | — | CN | claimed |
| CN-119816088-A | Perovskite passivation material, passivation layer film, preparation method of perovskite passivation material and passivation layer film, and perovskite solar cell | 中国华能集团清洁能源技术研究院有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-110234628-B | Process for preparing methoxymethyl pyridine dicarboxylic acid ester | 阿达玛阿甘有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-117820214-A | Process for preparing methoxymethyl pyridine dicarboxylic acid ester | 阿达玛阿甘有限公司 | 2024-04-05 | — | — | CN | disclosed |
| EP-4001266-A2 | PROCESS FOR PREPARING METHOXY METHYL PYRIDINE DICARBOXYLATE | Adama Agan Ltd. (IL) | 2022-05-25 | — | — | EP | disclosed |
| CN-110993798-B | Perovskite type solar cell based on synergistic post-treatment of multiple ammonium salts and preparation thereof | 北京大学 | 2021-11-19 | — | — | CN | disclosed |
| US-10669254-B2 | Process for preparing methoxy methyl pyridine dicarboxylate | ADAMA AGAN LTD. (IL) | 2020-06-02 | — | — | US | disclosed |
| CN-110993798-A | Perovskite type solar cell based on cooperative post-treatment of multiple ammonium salts and preparation method thereof | 北京大学 | 2020-04-10 | — | — | CN | disclosed |
| EP-3541787-A1 | PROCESS FOR PREPARING METHOXY METHYL PYRIDINE DICARBOXYLATE | Adama Agan Ltd. (IL) | 2019-09-25 | — | — | EP | disclosed |
| CN-110234628-A | Method for preparing methoxymethyl pyridine dicarboxylic acid ester | 阿达玛阿甘有限公司 | 2019-09-13 | — | — | CN | disclosed |
| US-9096570-B2 | Process for manufacturing substituted 3-pyridylmethyl ammonium bromides | BASF SE (DE) | 2015-08-04 | — | — | US | disclosed |
| US-9096570-B2 | Process for manufacturing substituted 3-pyridylmethyl ammonium bromides | BASF SE (DE) | 2015-08-04 | — | — | US | disclosed |
| CN-102245576-B | Process for manufacturing substituted 3-pyridylmethyl ammonium bromides | BASF SE | 2014-11-05 | — | — | CN | disclosed |
| CN-102245576-A | Process for manufacturing substituted 3-pyridylmethyl ammonium bromides | BASF SE | 2011-11-16 | — | — | CN | disclosed |
| EP-2365965-A1 | Process for manufacturing substituted 3-pyridylmethyl ammonium bromides | BASF SE (DE) | 2011-09-21 | — | — | EP | disclosed |
| EP-2365965-A1 | Process for manufacturing substituted 3-pyridylmethyl ammonium bromides | BASF SE (DE) | 2011-09-21 | — | — | EP | disclosed |
| US-20110224433-A1 | Process for Manufacturing Substituted 3-pyridylmethyl Ammonium Bromides | BASF SE (DE) | 2011-09-15 | — | — | US | disclosed |
| US-20110224433-A1 | Process for Manufacturing Substituted 3-pyridylmethyl Ammonium Bromides | BASF SE (DE) | 2011-09-15 | — | — | US | disclosed |
| WO-2010055139-A1 | PROCESS FOR MANUFACTURING SUBSTITUTED 3-PYRIDYLMETHYL AMMONIUM BROMIDES | BASF SE (DE) | 2010-05-20 | — | — | WO | disclosed |