Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 8/20 | 0.45 |
| ▸ | CHRND | Q07001 | 5/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | NPY4R | P50391 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21908048 | 1.00 | PTPN1 (0.49) | PTPN1GRIA1CHRNDCHRNA1CHRNG | |
| SCHEMBL19372396 | 1.00 | PTPN1 (0.49) | PTPN1GRIA1CHRNDCHRNA1CHRNG | |
| SCHEMBL24049222 | 1.00 | PTPN1 (0.49) | PTPN1GRIA1CHRNDCHRNA1CHRNG | |
| SCHEMBL19372615 | 1.00 | PTPN1 (0.49) | PTPN1GRIA1CHRNDCHRNA1CHRNG | |
| SCHEMBL19102248 | 0.97 | GRIA1 (0.47) | PTPN1GRIA1CHRNDCHRNA1CHRNG | |
| SCHEMBL19365106 | 0.97 | PTPN1 (0.52) | PTPN1GRIA1CHRNDCHRNA1CHRNG | |
| SCHEMBL16508316 | 0.97 | GRIA1 (0.47) | PTPN1GRIA1CHRNDCHRNA1CHRNG | |
| SCHEMBL19102254 | 0.97 | PTPN1 (0.52) | PTPN1GRIA1CHRNDCHRNA1CHRNG | |
| SCHEMBL16508315 | 0.97 | PTPN1 (0.52) | PTPN1GRIA1CHRNDCHRNA1CHRNG | |
| SCHEMBL21040692 | 0.96 | PTPN1 (0.53) | PTPN1GRIA1CHRNDCHRNA1CHRNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210363161-A1 | NITROGEN-CONTAINING MACROCYCLIC CONJUGATES AS RADIOPHARMACEUTICALS | CLARITY PHARMACEUTICALS LTD. (AU) | 2021-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210363161-A1 | NITROGEN-CONTAINING MACROCYCLIC CONJUGATES AS RADIOPHARMACEUTICALS | NCL, NUDC, C3AR1 | PTPN1 2606/4885GRIA1 1840/4885CHRND 3598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.