⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11989375 | 1.00 | — | — | |
| SCHEMBL4458592 | 1.00 | — | — | |
| SCHEMBL1367536 | 0.92 | — | — | |
| SCHEMBL15184925 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL28852943 | 0.89 | — | — | |
| SCHEMBL30277117 | 0.78 | — | — | |
| SCHEMBL26170815 | 0.71 | GAA (0.35) | — | |
| SCHEMBL254419 | 0.69 | — | — | |
| SCHEMBL9501843 | 0.69 | — | — | |
| SCHEMBL292798 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145012-A1 | PURINONES AS UBIQUITIN-SPECIFIC PROTEASE 1 INHIBITORS | FORMA THERAPEUTICS, INC. | 2017-05-25 | — | — | US | disclosed |
| US-8569515-B2 | Directed synthesis of oligophosphoramidate stereoisomers | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| EP-2370450-A1 | DIRECTED SYNTHESIS OF OLIGOPHOSPHORAMIDATE STEREOISOMERS | Roche Diagnostics GmbH (DE) | 2011-10-05 | — | — | EP | disclosed |
| US-20110212861-A1 | DIRECTED SYNTHESIS OF OLIGOPHOSPHORAMIDATE STEREOISOMERS | ROCHE DIAGNOSTICS GMBH (DE) | 2011-09-01 | — | — | US | disclosed |
| WO-2010060599-A1 | DIRECTED SYNTHESIS OF OLIGOPHOSPHORAMIDATE STEREOISOMERS | ROCHE DIAGNOSTICS GMBH (DE) | 2010-06-03 | — | — | WO | disclosed |
| WO-2003051899-A1 | DEAZAPURINE NUCLEOSIDE LIBRARIES AND COMPOUNDS | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |
| WO-2001038561-A1 | METHODS OF USE OF PEPTIDE DEFORMYLASE INHIBITORS AS NOVEL ANTIBACTERIAL AGENTS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2001-05-31 | — | — | WO | disclosed |
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |