SCHEMBL2405780

SCHEMBL2405780

Cc1ccccc1C(=O)Oc1cccc2cccc(OC(=O)C3CCCCC3C)c12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.44
MEN1 O00255 4/20 0.44
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
PKM P14618 1/20 0.41
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TAS1R3 Q7RTX0 3/20 0.38
TAS1R1 Q7RTX1 3/20 0.38
TAS1R2 Q8TE23 3/20 0.38
RAB9A P51151 3/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NPC1 O15118 3/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2407468 0.87 MEN1 (0.43) KMT2AMEN1ESR1ESR2TAS1R3
SCHEMBL2405408 0.85 KMT2A (0.48) KMT2AMEN1ESR1ESR2PKM
SCHEMBL2409027 0.85 KMT2A (0.44) KMT2AMEN1ESR1ESR2CYP2C9
SCHEMBL2406081 0.83 KMT2A (0.47) KMT2AMEN1ESR1ESR2CYP2C9
SCHEMBL2402715 0.82 KMT2A (0.50) KMT2AMEN1ESR1ESR2PKM
SCHEMBL2405044 0.82 KMT2A (0.42) KMT2AMEN1ESR1ESR2PKM
SCHEMBL20646377 0.82 KMT2A (0.61) KMT2AMEN1ESR1ESR2PKM
SCHEMBL2404246 0.81 KMT2A (0.46) KMT2AMEN1ESR1ESR2CYP3A4
SCHEMBL18035780 0.81 MYC (0.40) KMT2AMEN1TAS1R3TAS1R1TAS1R2
SCHEMBL2407032 0.81 KMT2A (0.43) KMT2AMEN1ESR1ESR2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP claimed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP claimed
US-9284392-B2 Mixed internal donor structures for 1-olefin polymerization catalysts BASF CORPORATION (US) 2016-03-15 US claimed
EP-2970521-A1 MIXED INTERNAL DONOR STRUCTURES FOR 1-OLEFIN POLYMERIZATION CATALYSTS BASF Corporation (US) 2016-01-20 EP claimed
EP-2782938-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF Corporation (US) 2014-10-01 EP claimed
WO-2014149628-A1 MIXED INTERNAL DONOR STRUCTURES FOR 1-OLEFIN POLYMERIZATION CATALYSTS BASF CORPORATION (US) 2014-09-25 WO claimed
US-20140275452-A1 MIXED INTERNAL DONOR STRUCTURES FOR 1-OLEFIN POLYMERIZATION CATALYSTS BASF CATALYSTS LLC (US) 2014-09-18 US claimed
WO-2013077837-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF CORPORATION (US) 2013-05-30 WO claimed
US-8318626-B2 Internal and external donor compounds for olefin polymerization catalysts III BASF CORPORATION (US) 2012-11-27 US claimed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US claimed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US claimed
US-20110213106-A1 Internal and External Donor Compounds for Olefin Polymerization Catalysts III BASF CATALYSTS LLC (US) 2011-09-01 US claimed
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP disclosed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP disclosed
US-9284392-B2 Mixed internal donor structures for 1-olefin polymerization catalysts BASF CORPORATION (US) 2016-03-15 US disclosed
EP-2970521-A1 MIXED INTERNAL DONOR STRUCTURES FOR 1-OLEFIN POLYMERIZATION CATALYSTS BASF Corporation (US) 2016-01-20 EP disclosed
US-8318626-B2 Internal and external donor compounds for olefin polymerization catalysts III BASF CORPORATION (US) 2012-11-27 US disclosed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US disclosed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US disclosed
US-20110213106-A1 Internal and External Donor Compounds for Olefin Polymerization Catalysts III BASF CATALYSTS LLC (US) 2011-09-01 US disclosed