SCHEMBL24059359

SCHEMBL24059359

Cc1cc(F)cc([C@@H](O)C(=O)Nc2ccc(-c3cnc(N)c(C(=O)NC(C)C)c3)c(C)c2)c1

nearest known ligand 0.92

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EIF2AK3 Q9NZJ5 19/20 0.92
EIF2S1 P05198 19/20 0.92

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29688002 0.96 EIF2AK3 (1.00) EIF2AK3EIF2S1
SCHEMBL29688162 0.96 EIF2AK3 (1.00) EIF2AK3EIF2S1
SCHEMBL29687742 0.96 EIF2AK3 (1.00) EIF2AK3EIF2S1
SCHEMBL23044519 0.96 EIF2AK3 (1.00) EIF2AK3EIF2S1
SCHEMBL30475705 0.96 EIF2AK3 (1.00) EIF2AK3EIF2S1
SCHEMBL29831258 0.96 EIF2AK3 (1.00) EIF2AK3EIF2S1
SCHEMBL29831260 0.96 EIF2AK3 (1.00) EIF2AK3EIF2S1
SCHEMBL23044599 0.96 EIF2AK3 (1.00) EIF2AK3EIF2S1
SCHEMBL20541830 0.96 EIF2AK3 (1.00) EIF2AK3EIF2S1
Fumaric Acid SCHEMBL30828818 0.91 EIF2AK3 (0.90) EIF2AK3EIF2S1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3612519-B1 PHENYL-2-HYDROXY-ACETYLAMINO-2-METHYL-PHENYL COMPOUNDS LILLY CO ELI (US) 2021-12-01 EP disclosed