Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.53 |
| ▸ | LCK | P06239 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17646016 | 0.87 | BTK (0.62) | BTKLCK | |
| SCHEMBL17645994 | 0.87 | BTK (0.66) | BTKLCK | |
| SCHEMBL17645974 | 0.83 | BTK (0.63) | BTKLCK | |
| SCHEMBL17645673 | 0.80 | BTK (0.80) | BTKLCK | |
| SCHEMBL17646050 | 0.79 | BTK (0.80) | BTKLCK | |
| SCHEMBL17646058 | 0.76 | BTK (0.59) | BTKLCK | |
| SCHEMBL17645868 | 0.76 | BTK (0.81) | BTKLCK | |
| SCHEMBL24061610 | 0.76 | BTK (0.56) | BTKLCK | |
| SCHEMBL17646005 | 0.76 | BTK (0.56) | BTKLCK | |
| SCHEMBL17645895 | 0.76 | BTK (0.81) | BTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204382-B1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2021-12-01 | — | — | EP | disclosed |