Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.39 |
| ▸ | CDK9 | P50750 | 3/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17645675 | 0.84 | BTK (0.59) | BTKCCNT1CDK9LCK | |
| SCHEMBL24061539 | 0.81 | BTK (0.57) | BTKLCK | |
| SCHEMBL24061669 | 0.79 | BTK (0.42) | BTKLCK | |
| SCHEMBL24061675 | 0.78 | BTK (0.52) | BTKLCK | |
| SCHEMBL24061702 | 0.78 | BTK (0.41) | BTKLCK | |
| SCHEMBL24061660 | 0.78 | BTK (0.41) | BTKLCK | |
| SCHEMBL17645952 | 0.75 | BTK (0.58) | BTKCCNT1CDK9LCK | |
| SCHEMBL17645683 | 0.74 | BTK (0.57) | BTKCCNT1CDK9LCK | |
| SCHEMBL17645760 | 0.74 | BTK (0.58) | BTKCCNT1CDK9LCK | |
| SCHEMBL17645648 | 0.74 | BTK (0.54) | BTKCCNT1CDK9LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204382-B1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2021-12-01 | — | — | EP | disclosed |