Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17645973 | 0.82 | BTK (0.65) | BTK | |
| SCHEMBL17645837 | 0.79 | BTK (0.79) | BTK | |
| SCHEMBL17645743 | 0.79 | BTK (0.70) | BTK | |
| SCHEMBL17645960 | 0.79 | BTK (0.80) | BTK | |
| SCHEMBL17645829 | 0.79 | BTK (0.80) | BTK | |
| SCHEMBL17645851 | 0.76 | BTK (0.46) | BTK | |
| SCHEMBL17645667 | 0.72 | BTK (0.81) | BTK | |
| SCHEMBL17645735 | 0.71 | BTK (0.81) | BTK | |
| SCHEMBL17645983 | 0.71 | BTK (0.81) | BTK | |
| SCHEMBL20878560 | 0.70 | BTK (0.66) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204382-B1 | HETEROARYL COMPOUNDS AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2021-12-01 | — | — | EP | disclosed |