Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 8/20 | 0.68 |
| ▸ | IKZF1 | Q13422 | 4/20 | 0.68 |
| ▸ | CRBN | Q96SW2 | 11/20 | 0.65 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24062132 | 0.88 | IKZF2 (0.78) | IKZF2IKZF1CRBNDDB1ALDH1A1 | |
| SCHEMBL25939860 | 0.87 | IKZF2 (0.77) | IKZF2IKZF1CRBNDDB1ALDH1A1 | |
| SCHEMBL25940952 | 0.85 | IKZF2 (0.64) | IKZF2IKZF1CRBNDDB1ALDH1A1 | |
| SCHEMBL24938087 | 0.84 | CRBN (0.76) | IKZF2IKZF1CRBNDDB1ALDH1A1 | |
| SCHEMBL24062344 | 0.83 | IKZF2 (0.69) | IKZF2IKZF1CRBNDDB1ALDH1A1 | |
| SCHEMBL24062266 | 0.83 | IKZF2 (0.66) | IKZF2IKZF1CRBNDDB1ALDH1A1 | |
| SCHEMBL24062350 | 0.83 | IKZF2 (0.66) | IKZF2IKZF1CRBNDDB1ALDH1A1 | |
| SCHEMBL21617663 | 0.83 | IKZF2 (0.69) | IKZF2IKZF1CRBNDDB1ALDH1A1 | |
| SCHEMBL24062302 | 0.83 | IKZF2 (0.69) | IKZF2IKZF1CRBNDDB1ALDH1A1 | |
| SCHEMBL24062242 | 0.83 | IKZF2 (0.66) | IKZF2IKZF1CRBNDDB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11185537-B2 | 3-(5-amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof | NOVARTIS AG (CH) | 2021-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11185537-B2 | 3-(5-amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof | RXFP3, RXFP1, NPY2R | IKZF2 3369/4885IKZF1 2611/4885CRBN 3123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.