Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964267 | 0.80 | MAPT (0.45) | LPAR1LPAR5ALDH1A1CHRM5CHRM1 | |
| SCHEMBL1969373 | 0.79 | LPAR1 (0.43) | LPAR1LPAR5KMT2AALDH1A1CHRM5 | |
| SCHEMBL1967192 | 0.77 | HCRTR1 (0.45) | KMT2AMEN1ALDH1A1CHRM5CHRM1 | |
| SCHEMBL1968841 | 0.77 | HCRTR1 (0.45) | LPAR1LPAR5KMT2AMEN1CYP3A4 | |
| SCHEMBL2405146 | 0.77 | RAF1 (0.44) | LPAR1LPAR5KMT2AMEN1CYP3A4 | |
| SCHEMBL1967545 | 0.77 | TP53 (0.44) | LPAR1LPAR5KMT2AMEN1CYP3A4 | |
| SCHEMBL1972116 | 0.77 | HCRTR1 (0.45) | CYP3A4CHRM5CHRM1CHRM3CYP1A2 | |
| SCHEMBL1966896 | 0.77 | KMT2A (0.46) | LPAR1LPAR5KMT2AMEN1CYP3A4 | |
| SCHEMBL1970480 | 0.76 | CHRM5 (0.42) | LPAR1LPAR5ALDH1A1CHRM5CHRM1 | |
| SCHEMBL2403444 | 0.75 | KMT2A (0.48) | LPAR1LPAR5KMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | HCRTR2, HCRTR1, HRH3 | LPAR1 186/4885LPAR5 400/4885KMT2A 253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.