SCHEMBL24063045

SCHEMBL24063045

Nc1ncnc2c(CN3CC(CSCc4ccccc4)[C@H](O)C3)c[nH]c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MTAP Q13126 16/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21067802 1.00 MTAP (1.00) MTAP
SCHEMBL12715583 1.00 MTAP (1.00) MTAP
SCHEMBL4736877 1.00 MTAP (1.00) MTAP
SCHEMBL4752750 0.91 MTAP (0.83) MTAP
SCHEMBL4736908 0.91 MTAP (0.83) MTAP
SCHEMBL12945171 0.89 MTAP (1.00) MTAP
SCHEMBL18975182 0.89 MTAP (1.00) MTAP
SCHEMBL24063155 0.88 MTAP (0.79) MTAP
SCHEMBL10064930 0.87 MTAP (0.77) MTAP
SCHEMBL4736743 0.85 MTAP (0.75) MTAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11186575-B2 Treatment of helicobacter pylori infections Alber Einslein College of Medicine (US) 2021-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11186575-B2 Treatment of helicobacter pylori infections MTAP, UNG, TPMT MTAP 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.